CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2119
Family Name Apoptosis regulator Bcl-2 Inhibitor N-phenyl-2,3,4-trihydroxy-5-benzyl-benzamide Family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00260315 Functional Category Investigative Drug
Superfamily Apoptosis regulator Bcl-2 and Induced myeloid leukemia cell differentiation protein Mcl-1 Binder Superfamily
Class Class 2356

Cousin Family NamesSeedsMembers
Apoptosis regulator Bcl-2 and Induced myeloid leukemia cell di... 1 1
Estradiol 17-beta-dehydrogenase 1 Inhibitor 2-hydroxy-n,6-bis(... 2 7
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 3
Benzamides Metabolite 2-(Ethylamino)-4,5-dihydroxybenzamide Fa... 1 0


External ID

Functional Category

Molecule Name

CFAMM00260312 CHEMBL47027 Bioactive 3,4,5-trihydroxy-N-[2-[(3,4,5-trihydroxybenzoyl)amino]phenyl]benzamide
CFAMM00260314 DNC006897 Investigative Drug 2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide
CFAMM00260315 DNC006896 Investigative Drug N-phenyl-2,3,4-trihydroxy-5-benzyl-benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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