CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2134
Family Name Melanin-concentrating hormone receptor 1 Ligand ADS-102891 Family
No. of Seeds 6 No. of Other Members 51
Family Centroid CFAMM00260710 Functional Category Investigative Drug
Superfamily Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 2246

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
SB1518 family 7 103
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Melanin-concentrating hormone receptor 1 Ligand Gnf-pf-2322 Fa... 3 95
D(2) dopamine receptor Ligand SLV-314 Family 19 69
Melanin-concentrating hormone receptor 1 Ligand ADS-103214 Family 3 4
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Metabotropic glutamate receptor 1 Ligand 4-(cyclohexyloxy)quin... 1 4
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 6 47
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
Survival motor neuron protein inhibitor CHEMBL1307497 family 1 2
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 8
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Methionine--tRNA ligase inhibitor SureCN7818675 family 7 14
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Fatty-acid amide hydrolase 1 inhibitor (1R)-2-[[6-(3-chloro-4-... 1 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
5-hydroxytryptamine receptor 1B and Alpha-2A adrenergic recept... 1 0
Melanin-concentrating hormone receptor 1 ligand (E)-N-[2-[4-(1... 1 1
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Renin and Cytochrome P450 3A4 inhibitor AGN-PC-046RG9 family 8 28
Epidermal growth factor receptor ligand SureCN2989664 family 5 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 18 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 18 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
Epidermal growth factor receptor ligand AGN-PC-07B1XF family 3 0
Melanin-concentrating hormone receptor 1 ligand (E)-N-[2-(4-cy... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00260728 CHEMBL2016730 Bioactive 2-(4-chlorophenoxy)-N-[4-methyl-2-[4-(propan-2-ylcarbamoylamino)piperidin-1-yl]quinazolin-6-yl]acetamide
CFAMM00260679 DNC006950 Investigative Drug ADS-103254
CFAMM00260714 DNC006948 Investigative Drug ADS-103293
CFAMM00260713 DNC006949 Investigative Drug ADS-103316
CFAMM00260711 DNC006945 Investigative Drug ADS-103253
CFAMM00260710 DNC006947 Investigative Drug ADS-102891

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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