CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2153
Family Name D(4) dopamine receptor Ligand A-425444 Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00261318 Functional Category Investigative Drug with Natural Product
Superfamily D(4) dopamine receptor Ligand A-425444 Superfamily
Class Class 1333

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
Tyrosine kinase Inhibitor PKI166 Family 17 198
Nitric oxide synthase, inducible Inhibitor 4-(1h-imidazol-1-yl... 1 7
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Platelet-derived growth factor receptor alpha and Platelet-der... 3 18
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Platelet-derived growth factor receptor beta and Platelet-deri... 2 19
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 3
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 1 3
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 5 8
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-07... 1 0
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Vascular endothelial growth factor receptor 2 and Vascular end... 4 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Tyrosine-protein kinase Lck inhibitor 3-[[2-(benzimidazol-1-yl... 2 0
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00261317 CHEMBL571483 Bioactive AGN-PC-077D4S
CFAMM00261318 DNC007023 Investigative Drug A-425444

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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