CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2155
Family Name Epidermal growth factor receptor and Abelson tyrosine-protein kinase 2 Inhibitor SKI-758 Family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00261353 Functional Category Investigative Drug
Superfamily Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-protein kinase Src Inhibitor Bosutinib Superfamily
Class Class 970

Cousin Family NamesSeedsMembers
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 67 130
Proto-oncogene tyrosine-protein kinase Src inhibitor AGN-PC-07... 17 9
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS94Q ... 6 0


External ID

Functional Category

Molecule Name

CFAMM00261354 CHEMBL276934 Bioactive SureCN3995550
CFAMM00261359 CHEMBL415625 Bioactive 4-(2,4-dichloro-5-methoxyanilino)-7-[5-[(4-methylpiperazin-1-yl)methyl]furan-2-yl]quinoline-3-carbonitrile
CFAMM00261352 CHEMBL219964 Bioactive AGN-PC-00B6YS
CFAMM00261357 CHEMBL278495 Bioactive AGN-PC-00DESO
CFAMM00261355 CHEMBL219260 Bioactive 4-(2,4-dichloro-5-methoxyanilino)-7-[5-[(4-methylpiperazin-1-yl)methyl]furan-3-yl]quinoline-3-carbonitrile
CFAMM00261353 DNC007028 Investigative Drug SKI-758

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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