CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2174
Family Name Leukotriene A-4 hydrolase Inhibitor 1-butoxy-4-phenoxybenzene Family
No. of Seeds 3 No. of Other Members 85
Family Centroid CFAMM00261682 Functional Category Investigative Drug with Human Metabolite
Superfamily Leukotriene A-4 hydrolase Inhibitor 1-butoxy-4-phenoxybenzene Superfamily
Class Class 2008

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Translocator protein Inhibitor Dextofisopam Family 3 250
Glycoprotein IIb/IIIa receptor Ligand Accutin Family 4 24
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Voltage-dependent L-type calcium channel subunit alpha-1D and ... 1 13
Collagenase 3 and Interstitial collagenase Inhibitor 3-(4-meth... 12 76
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 1,1,... 2 8
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 6-ph... 1 18
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor 1,4-ph... 3 9
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
Carbonic anhydrase 2 Inhibitor Guaiacol Family 1 14
Leukotriene A-4 hydrolase Inhibitor (r/s)-2-((4-phenoxyphenoxy... 7 18
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-meth... 4 12
Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tol... 4 11
Beta-secretase 1 Inhibitor Eckol Family 6 40
Prostaglandin G/H synthase 1 Inhibitor Acetic Acid 2-heptylsel... 1 14
4-hydroxyphenylpyruvate dioxygenase Inhibitor (4-hydroxy-pheno... 1 13
Prostaglandin G/H synthase 1 Inhibitor 2-(2-methoxyphenyl)-1h-... 1 11
Survival motor neuron protein and Lysine-specific demethylase ... 1 16
Prelamin-A/C and Solute carrier organic anion transporter fami... 1 15
Squalene synthase inhibitor [4-[3-(propan-2-ylamino)propoxy]ph... 1 3
Amine oxidase [flavin-containing] B inhibitor 4-[4-[(3-chlorop... 2 3
Beta-lactamase inhibitor AGN-PC-0A9UJZ family 1 3
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor 6-[te... 1 0
Cannabinoid receptor 1 and Monoglyceride lipase ligand 4-(4-ph... 4 4
D-amino-acid oxidase inhibitor 5-hydroxy-2-(phenoxymethyl)pyra... 2 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 1
Phenylacetic Acid Derivatives Metabolite 3,4,5-Trimethoxypheny... 1 7
Benzo-p-Dioxins Metabolite 1,4-Benzodioxin-2(3H)-one Family 1 3
Benzene and Substituted Derivatives Metabolite 1,3,5-Trimethox... 2 17


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00261682 DNC009618 Investigative Drug 1-butoxy-4-phenoxybenzene
CFAMM00261680 DNC007108 Investigative Drug NSC-2113
CFAMM00261683 DNC009619 Investigative Drug 1-(pentyloxy)-4-phenoxybenzene

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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