CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2181
Family Name Cathepsin K Inhibitor 2-cyclohexylamino-pyridine-2-carbonitrile Family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00261852 Functional Category Investigative Drug
Superfamily Cathepsin K Inhibitor 2-cyclohexylamino-pyridine-2-carbonitrile Superfamily
Class Class 2379

Cousin Family NamesSeedsMembers
SUR2-type K(ATP) channel Ligand Pinacidil Family 1 8
Carbonic anhydrase 2 Inhibitor Cyanamide Family 2 32
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Adenosine receptor A1 and Adenosine receptor A2a Ligand 3-benz... 1 6
Cyclin-dependent kinase 2 and Mitogen-activated protein kinase... 7 30
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-amin... 2 30
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-amin... 4 11
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 9 24
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 9
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
S-adenosylmethionine decarboxylase proenzyme inhibitor 6-[(E)-... 2 6
Bloom syndrome protein inhibitor SR 57227A family 2 12
Histamine H4 receptor ligand 4-[(3R)-3-(methylamino)pyrrolidin... 7 6
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1
Acetylcholinesterase and Cholinesterase inhibitor 2-amino-6-[3... 1 4
Farnesyl pyrophosphate synthase inhibitor AC1NQOV1 family 2 1
Microtubule-associated protein tau and Thyrotropin receptor li... 1 2
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00261852 DNC007117 Investigative Drug 2-cyclohexylamino-pyridine-2-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26195 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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