CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2184
Family Name L-selectin and P-selectin Inhibitor 2,3,4-trihydroxybenzoic Acid Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00261875 Functional Category Investigative Drug with Natural Product
Superfamily L-selectin and P-selectin Binder Superfamily
Class Class 121

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Prostaglandin G/H synthase 1 Inhibitor Salicyclic Acid Family 3 39
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Danthron family 11 141
taste receptor Ligand Cynarin Family 6 124
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Mitogen-activated protein kinase 12 Inhibitor SCIO-469 Family 1 7
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Arachidonate 5-lipoxygenase Inhibitor Caffeic Acid Family 3 32
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Apoptosis regulator Bcl-2 Inhibitor Gossypol Family 1 9
Endothelin-1 receptor Ligand PD156707 Family 41 211
Macrophage migration inhibitory factor and Prothrombin Inhibit... 2 49
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 2 19
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
Steryl-sulfatase Inhibitor Sulfamic Acid 3-(4-hydroxy-benzoyl)... 3 2
Protein kinase C alpha type and Protein kinase C beta type Inh... 7 1
Epidermal growth factor receptor Ligand AG-538 Family 5 11
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
4-aminobutyrate aminotransferase, mitochondrial and Succinate-... 4 22
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Platelet-derived growth factor receptor beta Ligand Bis(5-meth... 5 220
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
DNA topoisomerase 2-beta Inhibitor Demethylzeylasterone Family 1 2
Protein kinase C alpha type and Protein kinase C beta type Inh... 2 1
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Indoleamine 2,3-dioxygenase 1 Inhibitor Garveatin E Family 2 0
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Amine oxidase [flavin-containing] B Inhibitor 4-oxo-4h-chromen... 2 3
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Isocitrate lyase Inhibitor Bis(3-bromo-4,5-dihydroxyphenyl)met... 1 2
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 6 13
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 2
3-phosphoshikimate 1-carboxyvinyltransferase inhibitor AGN-PC-... 1 0
Tyrosine-protein kinase Lck and Tyrosine-protein kinase Fyn in... 1 2
Catechol O-methyltransferase inhibitor 4,5-dihydroxybenzene-1,... 1 1
Prenol Lipids Metabolite Scutigeral Family 1 0
1-(3,5-dihydroxyphenyl)-12-hydroxytridecan-2-one NP ZINC311562... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00261876 DNC007143 Investigative Drug GALLICACID
CFAMM00261875 DNC007142 Investigative Drug 2,3,4-trihydroxybenzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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