CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2194
Family Name Liver carboxylesterase 1 Inhibitor 4-chloro-1h-indole-2,3-dione Family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00262127 Functional Category Investigative Drug
Superfamily Liver carboxylesterase 1 and Cruzipain Binder Superfamily
Class Class 1607

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Serum albumin Inhibitor Ebselen Family 3 62
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Glutamate receptor ionotropic, NMDA 1 Ligand Dcka, 5,7-dichlor... 2 7
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
Cruzipain Inhibitor 5-chloro-1-(4-chloro-benzyl)-1h-indole-2,3... 3 13
Liver carboxylesterase 1 Inhibitor 7-chloro-1h-indole-2,3-dion... 6 5
Liver carboxylesterase 1 Inhibitor 7-(trifluoromethyl)-1h-indo... 1 1
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(2,4... 3 6
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
Muscarinic acetylcholine receptor M1 and Beta-lactamase ligand... 1 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00262127 DNC007200 Investigative Drug 4-chloro-1H-indole-2,3-dione
CFAMM00262126 DNC007190 Investigative Drug 4-chloro-7-methyl-1H-indole-2,3-dione
CFAMM00262124 DNC007194 Investigative Drug 4,6-dichloro-1H-indole-2,3-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26825 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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