CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2195
Family Name Liver carboxylesterase 1 Inhibitor 7-chloro-1h-indole-2,3-dione Family
No. of Seeds 6 No. of Other Members 5
Family Centroid CFAMM00262134 Functional Category Investigative Drug with Natural Product
Superfamily Liver carboxylesterase 1 and Cruzipain Binder Superfamily
Class Class 1607

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Serum albumin Inhibitor Ebselen Family 3 62
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
Cruzipain Inhibitor 5-chloro-1-(4-chloro-benzyl)-1h-indole-2,3... 3 13
MO15-related protein kinase Pfmrk Inhibitor 5-nitro-1h-indole-... 1 4
Liver carboxylesterase 1 Inhibitor 6-bromo-5-methyl-1h-indole-... 1 0
Liver carboxylesterase 1 Inhibitor 4-chloro-1h-indole-2,3-dion... 3 7
Liver carboxylesterase 1 Inhibitor 7-(trifluoromethyl)-1h-indo... 1 1
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 8
Aldose reductase inhibitor Spiro-cimqat family 6 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00262138 DNC007191 Investigative Drug 6,7-dichloro-1H-indole-2,3-dione
CFAMM00262137 DNC007192 Investigative Drug 5,7-dichloro-1H-indole-2,3-dione
CFAMM00262136 DNC007193 Investigative Drug 4,7-dichloro-1H-indole-2,3-dione
CFAMM00262135 DNC007195 Investigative Drug 4,5-dichloro-1H-indole-2,3-dione
CFAMM00262134 DNC007197 Investigative Drug 7-chloro-1H-indole-2,3-dione
CFAMM00262140 DNC007199 Investigative Drug 5-chloro-1H-indole-2,3-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48694 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543