CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2197
Family Name Liver carboxylesterase 1 Inhibitor 5-(trifluoromethoxy)-1h-indole-2,3-dione Family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00262156 Functional Category Investigative Drug with Natural Product
Superfamily Peroxisome proliferator-activated receptor gamma Ligand Rosiglitazone & Simvastatin Superfamily
Class Class 704

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Cruzipain Inhibitor 1-(3-methoxy-benzyl)-5-methyl-1h-indole-2,... 2 11
MO15-related protein kinase Pfmrk Inhibitor 3-[3-(2-hydroxy-et... 1 6
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 16
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Protease inhibitor AC1LALME family 2 1
Melanin-concentrating hormone receptor 1 and Potassium voltage... 3 6
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 6 3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00262151 CHEMBL2381694 Bioactive 1-(2-phenoxyethyl)-5-(trifluoromethoxy)indole-2,3-dione
CFAMM00262156 DNC007198 Investigative Drug 5-(trifluoromethoxy)-1H-indole-2,3-dione
CFAMM00262155 DNC009704 Investigative Drug VU0238429

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43615 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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