CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2214
Family Name DNA-dependent protein kinase catalytic subunit Inhibitor 2-(1h-indol-5-yl)-6-morpholino-4h-pyran-4-one Family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00262251 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 3A Ligand Dolasetron Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
Histamine H1 receptor Ligand Doxylamine Family 2 91
5-hydroxytryptamine receptor Ligand Metergolin Family 2 11
Grt 6005/06 family 4 22
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 18 17
Melanin-concentrating hormone receptor 1 ligand 4-[(2-fluoroph... 3 0
D(1A) dopamine receptor and D(3) dopamine receptor ligand RU-2... 3 4
CGMP-dependent protein kinase inhibitor AGN-PC-0761UG family 1 2


External ID

Functional Category

Molecule Name

CFAMM00262251 DNC007246 Investigative Drug 2-(1H-indol-5-yl)-6-morpholino-4H-pyran-4-one
CFAMM00262250 DNC007252 Investigative Drug 2-morpholino-6-(quinolin-8-yl)-4H-pyran-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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