CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2230
Family Name Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-one Family
No. of Seeds 3 No. of Other Members 69
Family Centroid CFAMM00262397 Functional Category Investigative Drug with Natural Product
Superfamily Aromatase Binder Superfamily
Class Class 1096

Cousin Family NamesSeedsMembers
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
Thromboxane-A synthase Inhibitor Dazoxiben Family 2 32
Nitric oxide synthase, inducible Inhibitor 4-(1h-imidazol-1-yl... 1 7
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Aromatase Inhibitor 3-((1h-imidazol-1-yl)methyl)-9h-xanthen-9-... 6 17
Aromatase Inhibitor 1-(7-methoxy-2-phenyl-chroman-4-yl)-1h-imi... 2 22
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 1-... 2 9
Aromatase Inhibitor 4'-cyano-3-(imidazolylmethyl)flavone Family 4 3
Aromatase Inhibitor 4-(2-(1h-imidazol-1-yl)ethoxy)-2h-chromen-... 2 6
Cytochrome P450 3A4 Inhibitor SK&F-96365 Family 2 26
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Rac-4'-(1-i... 5 9
Cytochrome P450 11B1, mitochondrial Inhibitor (3-((1h-imidazol... 2 5
Aromatase Inhibitor 1-(4-nitro-2-phenoxybenzyl)-1h-imidazole F... 1 4
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(2-phenoxy-eth... 1 10
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 18
Beta-1 adrenergic receptor ligand 1-[4-[2-(5-bromo-1H-imidazol... 3 8
Aromatase inhibitor AGN-PC-075MOK family 1 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 2
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor 3-[6-[(... 14 26
3-oxoacyl-[acyl-carrier-protein] synthase 3 inhibitor 1-(2-met... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Aromatase inhibitor 4-[(Z)-1-(3,5-dimethoxyphenyl)-3-imidazol-... 1 2
Aromatase inhibitor AGN-PC-093P98 family 1 3
Delta-type opioid receptor and Kappa-type opioid receptor liga... 2 0
Pol polyprotein inhibitor 162540-49-0 family 1 2
Thromboxane A2 receptor and Thromboxane-A synthase ligand 5-[(... 1 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 4 6
Alpha-1A adrenergic receptor ligand AGN-PC-0793UT family 3 3
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 0
Glutaminyl-peptide cyclotransferase inhibitor thioamide deriv.... 1 1
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00262399 DNC007305 Investigative Drug 7-((1H-imidazol-1-yl)methyl)-2H-chromen-2-one
CFAMM00262397 DNC007302 Investigative Drug 4-((1H-imidazol-1-yl)methyl)-2H-chromen-2-one
CFAMM00262455 DNC010873 Investigative Drug 1-(2-phenoxybenzyl)-1H-imidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26823 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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