CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2236
Family Name Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-phenylurea Family
No. of Seeds 4 No. of Other Members 44
Family Centroid CFAMM00262563 Functional Category Investigative Drug
Superfamily Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-phenylurea Superfamily
Class Class 2396

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1-[bis(4-iodophenyl)methyl]-3-(4... 4 13
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 13
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
DNA topoisomerase Inhibitor 6-(3-iodo-phenylamino)-1h-pyrimidi... 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C8 inhib... 6 5
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 2 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 7 18
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 2 8
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,3,4-trifluorop... 2 2
Melanin-concentrating hormone receptor 1 ligand SureCN3845324 ... 7 4
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanin-concentrating hormone receptor 1 ligand SureCN14265866... 11 2
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 2
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00CYMY ... 1 0
Inosine-5'-monophosphate dehydrogenase inhibitor 1-[4-chloro-3... 3 5
Inosine-5'-monophosphate dehydrogenase inhibitor 1-(3,4-dichlo... 1 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-(2-... 1 0
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 14 5
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(4-c... 1 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(3,5... 2 0
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 4 0
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
Melanin-concentrating hormone receptor 1 ligand 1-[4-chloro-3-... 1 1
Neuropeptide Y receptor type 5 ligand SureCN6214451 family 3 1
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9352718 f... 2 3
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2
Melanin-concentrating hormone receptor 1 ligand N-[1-[3-(4-chl... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 2 0
Glycogen phosphorylase, liver form inhibitor TCMDC-135759 family 1 0
P2X purinoceptor 7 inhibitor N-(4-chlorophenyl)-4-[(Z)-1-(2-me... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00262547 DNC014628 Investigative Drug 1-(4-Chloro-phenyl)-3-(3,3-diphenyl-allyl)-urea
CFAMM00262593 DNC007319 Investigative Drug 1-[bis(4-chlorophenyl)methyl]-3-phenylthiourea
CFAMM00262549 DNC007321 Investigative Drug 1-[bis(4-chlorophenyl)methyl]-3-(4-chlorophenyl)-
CFAMM00262563 DNC007317 Investigative Drug 1-(bis(4-chlorophenyl)methyl)-3-phenylurea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27430 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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