CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2245
Family Name Plasminogen and Urokinase-type plasminogen activator Inhibitor 1-guanidino-7-isoquinolinesulphonamide Family
No. of Seeds 3 No. of Other Members 26
Family Centroid CFAMM00262941 Functional Category Investigative Drug
Superfamily Plasminogen and Prostaglandin G/H synthase 1 Binder Superfamily
Class Class 433

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Rho-associated protein kinase 1 Inhibitor Rho-kinase Inhibitor... 6 39
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
Prostaglandin G/H synthase 1 Inhibitor 1-(4-aminosulfonylpheny... 3 18
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor PF-91... 8 14
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 5 10
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8
Urokinase-type plasminogen activator and Tissue-type plasminog... 3 15
Urokinase-type plasminogen activator and Plasminogen inhibitor... 6 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 4-(4-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00262941 DNC007349 Investigative Drug 1-guanidino-7-isoquinolinesulphonamide
CFAMM00262955 DNC007350 Investigative Drug 4-chloro-1-guanidino-7-isoquinolinesulphonamide
CFAMM00262954 DNC007351 Investigative Drug 1-guanidino-N-phenyl-7-isoquinolinesulphonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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