CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2260
Family Name Arachidonate 5-lipoxygenase Inhibitor N-(thiazol-2-yl)benzamide Family
No. of Seeds 3 No. of Other Members 53
Family Centroid CFAMM00263682 Functional Category Investigative Drug with Natural Product
Superfamily Arachidonate 5-lipoxygenase Binder Superfamily 3
Class Class 2402

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Metabotropic glutamate receptor 5 Ligand 3-chloro-n-(4-methylt... 2 12
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor 7-me... 3 14
Arachidonate 5-lipoxygenase Inhibitor 2-phenyl-n-(thiazol-2-yl... 3 27
Mitogen-activated protein kinase 11 and Mitogen-activated prot... 10 31
Adenosine receptor A1 Ligand N-(4-phenyl-thiazol-2-yl)-benzami... 5 2
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Acyl-CoA desaturase and Acyl-CoA desaturase 1 Inhibitor MF-152... 2 1
Reverse transcriptase Inhibitor LY-73497 Family 14 5
Adenosine receptor A1 Ligand 4-chloro-n-(4-phenyl-thiazol-2-yl... 4 2
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Neuropeptide Y receptor type 5 ligand 3-[[5-(2-methylbenzoyl)-... 2 8
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
D(4) dopamine receptor ligand Benzamide, 3-methyl-N-[[4-(2-thi... 2 1
Niemann-Pick C1 protein and Survival motor neuron protein inhi... 1 2
Tyrosine-protein kinase ABL1 inhibitor AGN-PC-04SU6B family 2 3
Methionine aminopeptidase and Methionine aminopeptidase 1 inhi... 3 7
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-03LEDF family 3 4
Type-1 angiotensin II receptor ligand AGN-PC-078Z3W family 1 0
Tyrosine-protein kinase ABL1 inhibitor F0344-0933 family 2 1
Cyclin-dependent kinase 5 and G1/S-specific cyclin-E1 inhibito... 2 1
Free fatty acid receptor 2 ligand (2S)-2-(4-chlorophenyl)-N-(5... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00263681 DNC007407 Investigative Drug 4-(dimethylamino)-N-(thiazol-2-yl)benzamide
CFAMM00263699 DNC007416 Investigative Drug N-(5-methylthiazol-2-yl)benzamide
CFAMM00263682 DNC007406 Investigative Drug N-(thiazol-2-yl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27405 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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