CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2262
Family Name Arachidonate 5-lipoxygenase Inhibitor 2-phenyl-n-(thiazol-2-yl)acetamide Family
No. of Seeds 3 No. of Other Members 27
Family Centroid CFAMM00263750 Functional Category Investigative Drug with Natural Product
Superfamily Arachidonate 5-lipoxygenase Binder Superfamily 3
Class Class 2402

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Arachidonate 5-lipoxygenase Inhibitor N-(thiazol-2-yl)benzamid... 3 53
Mitogen-activated protein kinase 11 and Mitogen-activated prot... 10 31
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Reverse transcriptase Inhibitor PT-316 Family 8 2
Reverse transcriptase Inhibitor LY-73497 Family 14 5
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
D(4) dopamine receptor ligand Benzamide, 3-methyl-N-[[4-(2-thi... 2 1
Glucocorticoid receptor and Progesterone receptor ligand CHEMB... 2 0
Glucokinase inhibitor AGN-PC-00F9PQ family 3 10
Type-1 angiotensin II receptor ligand AGN-PC-078Z3W family 1 0
Cyclin-dependent kinase 5 and G1/S-specific cyclin-E1 inhibito... 2 1
Free fatty acid receptor 2 ligand (2S)-2-(4-chlorophenyl)-N-(5... 3 0


External ID

Functional Category

Molecule Name

CFAMM00263770 CHEMBL1800979 Bioactive 2,2-dimethyl-3,3-diphenyl-N-(1,3-thiazol-2-yl)propanamide
CFAMM00263750 DNC007409 Investigative Drug 2-phenyl-N-(thiazol-2-yl)acetamide
CFAMM00263775 DNC007413 Investigative Drug N-(5-methylthiazol-2-yl)-2-phenylacetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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