CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2270
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Inhibitor 3-(4-morpholinothieno[3,2-d]pyrimidin-2-yl)phenol Family
No. of Seeds 8 No. of Other Members 11
Family Centroid CFAMM00263981 Functional Category Investigative Drug
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Inhibitor CUDC-907 Superfamily
Class Class 1154

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 53
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 11
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 17
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00263996 CHEMBL493083 Bioactive SureCN12464157
CFAMM00263979 CHEMBL493289 Bioactive 3-[6-[(dimethylamino)methyl]-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl]phenol
CFAMM00263985 CHEMBL510164 Bioactive Compound 15e
CFAMM00263991 CHEMBL523379 Bioactive PI-540
CFAMM00263990 CHEMBL493290 Bioactive 3-[6-[[2-methoxyethyl(methyl)amino]methyl]-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl]phenol
CFAMM00263983 CHEMBL522031 Bioactive SureCN959505
CFAMM00263988 CHEMBL1086923 Bioactive AGN-PC-00BXNQ
CFAMM00263981 DNC007444 Investigative Drug 3-(4-morpholinothieno[3,2-d]pyrimidin-2-yl)phenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

25231 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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