CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2271
Family Name Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fluorobenzoate Family
No. of Seeds 5 No. of Other Members 18
Family Centroid CFAMM00264010 Functional Category Investigative Drug with Natural Product
Superfamily Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fluorobenzoate Superfamily
Class Class 237

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Histamine H1 receptor Ligand Terfenadine Family 3 50
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
D(2) dopamine receptor Ligand Haloperidol Family 5 53
Muscarinic acetylcholine receptor Ligand Flutropium Bromide Fa... 6 45
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Muscarinic acetylcholine receptor Ligand Mepenzolate Family 35 11
Muscarinic acetylcholine receptor M1 Ligand Oxyphenonium Family 12 5
Mu-type opioid receptor Ligand Diphenoxylate Family 5 6
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 1 6
Sodium-dependent noradrenaline transporter Inhibitor (r)-1-((s... 3 8
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor [(1R)-1-(... 2 5
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 1
Peptidyl-prolyl cis-trans isomerase FKBP1A and Peptidyl-prolyl... 4 27
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 18
Sodium-dependent serotonin transporter and Transporter inhibit... 6 9
Sigma non-opioid intracellular receptor 1 ligand SureCN5315520... 3 11
5-hydroxytryptamine receptor 1A ligand SureCN7763400 family 4 9
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-04TFA0... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 1
Sodium-dependent serotonin transporter and Transporter inhibit... 2 4
Sodium-dependent serotonin transporter and Transporter inhibit... 4 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 2 3
C-C chemokine receptor type 5 ligand AC1NUL4I family 2 0
C-C chemokine receptor type 5 ligand AC1LAX0N family 2 0
Histamine H1 receptor and 5-hydroxytryptamine receptor 2C liga... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand (4aR,... 1 0
Acetylcholine-binding protein and Soluble acetylcholine recept... 1 2
ATP-sensitive inward rectifier potassium channel 1 and Potassi... 3 3
Huntingtin and Inositol monophosphatase 1 inhibitor CHEMBL1493... 1 1


External ID

Functional Category

Molecule Name

CFAMM00264011 DNC007448 Investigative Drug 4-[4-(benzyloxy)piperidino]butyl-3-chlorobenzoate
CFAMM00264010 DNC007447 Investigative Drug 4-[4-(benzyloxy)piperidino]butyl-3-fluorobenzoate
CFAMM00264016 DNC007451 Investigative Drug 4-[4-(benzyloxy)piperidino]butyl-4-chlorobenzoate
CFAMM00264015 DNC007450 Investigative Drug 4-[4-(benzyloxy)piperidino]butyl-4-fluorobenzoate
CFAMM00264007 DNC013292 Investigative Drug 4-[4-(benzhydryloxy)piperidino]butyl benzoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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