CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2275
Family Name Vascular endothelial growth factor receptor 2 Ligand 3-(4-aminophenyl)thieno[3,2-c]pyridin-4-amine Family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00264099 Functional Category Investigative Drug
Superfamily Vascular endothelial growth factor receptor 2 Ligand 3-(4-aminophenyl)thieno[3,2-c]pyridin-4-amine Superfamily
Class Class 1151

Cousin Family NamesSeedsMembers
Aurora kinase A Inhibitor ABT-348 Family 20 49
5-hydroxytryptamine receptor Ligand Sl65.0472 Family 2 16
Platelet-derived growth factor receptor alpha and Platelet-der... 5 48
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 1 9
Cytochrome P450 3A4 Inhibitor 3-(3-methylthiophen-2-yl)pyridin... 5 27
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 16
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
D(2) dopamine receptor Ligand PD-135146 Family 5 11
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Reverse transcriptase Inhibitor HI-443 Family 1 0
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 2 7
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Platelet-activating factor receptor ligand Foropafant family 2 0
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 5 0
Vascular endothelial growth factor receptor 2 ligand AC1NS6KN ... 4 5
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Protein-cysteine N-palmitoyltransferase porcupine inhibitor 2-... 5 2
Transient receptor potential cation channel subfamily V member... 1 0
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 1 0
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Vascular endothelial growth factor receptor 2 ligand Thienopyr... 2 2
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Metabotropic glutamate receptor 5 ligand AGN-PC-075XWO family 2 0
Glutamate racemase inhibitor (5Z)-N-methyl-5-pyrrol-3-ylidene-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00264099 DNC007461 Investigative Drug 3-(4-aminophenyl)thieno[3,2-c]pyridin-4-amine
CFAMM00264106 DNC010251 Investigative Drug 4-(piperazin-1-yl)thieno[3,2-c]pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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