CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2279
Family Name Plasmepsin-2 Inhibitor KNI-10079 Family
No. of Seeds 19 No. of Other Members 8
Family Centroid CFAMM00264173 Functional Category Investigative Drug
Superfamily Plasmepsin-2 Binder Superfamily
Class Class 2410

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Lopinavir Family 4 25
Plasmepsin-2 Inhibitor KNI-727 Family 3 37
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Plasmepsin-2 Inhibitor KNI-10314 Family 6 2
Plasmepsin-2 Inhibitor KNI-10283 Family 24 0
Plasmepsin-2 Inhibitor KNI-10074 Family 1 0
E3 ubiquitin-protein ligase XIAP inhibitor N-METHYLALANYL-3-ME... 3 14
Pol polyprotein inhibitor MK-944a family 6 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(4S)-3... 3 24
Pol polyprotein inhibitor (2R)-2-benzyl-5-[(3S,5R)-3-benzyl-5-... 11 5
Pol polyprotein inhibitor L-689,502 family 17 2
Pol polyprotein inhibitor SDZ PRI 053 family 8 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2-me... 4 0
Pol polyprotein inhibitor (2R)-5-[(3S,5R)-3,5-dibenzyl-2-oxopy... 3 0


External ID

Functional Category

Molecule Name

CFAMM00264177 DNC009304 Investigative Drug KNI-10093
CFAMM00264183 DNC009320 Investigative Drug KNI-10260
CFAMM00264200 DNC009310 Investigative Drug KNI-10124
CFAMM00264176 DNC009303 Investigative Drug KNI-10092
CFAMM00264190 DNC007478 Investigative Drug KNI-10006
CFAMM00264199 DNC009311 Investigative Drug KNI-10125
CFAMM00264182 DNC009323 Investigative Drug KNI-10155
CFAMM00264175 DNC009302 Investigative Drug KNI-10081
CFAMM00264181 DNC009322 Investigative Drug KNI-10266
CFAMM00264174 DNC009301 Investigative Drug KNI-10080
CFAMM00264180 DNC009307 Investigative Drug KNI-10216
CFAMM00264197 DNC007492 Investigative Drug KNI-10062
CFAMM00264173 DNC009300 Investigative Drug KNI-10079
CFAMM00264179 DNC009306 Investigative Drug KNI-10369
CFAMM00264170 DNC009309 Investigative Drug KNI-10113
CFAMM00264178 DNC009305 Investigative Drug KNI-10094
CFAMM00264169 DNC009308 Investigative Drug KNI-10217
CFAMM00264184 DNC009321 Investigative Drug KNI-10152
CFAMM00264202 DNC009318 Investigative Drug KNI-10265

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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