CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2280
Family Name Plasmepsin-2 Inhibitor KNI-10526 Family
No. of Seeds 8 No. of Other Members 10
Family Centroid CFAMM00264220 Functional Category Investigative Drug
Superfamily Plasmepsin-2 Binder Superfamily
Class Class 2410

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Indinavir Family 36 211
Renin and Pepsin A inhibitor [(2S)-1-[[(2R)-1-[[(2S,3R)-1-cycl... 2 2
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Pol polyprotein and Renin inhibitor U-75875 family 12 1
Pol polyprotein inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-... 7 3
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 4 4
Beta-secretase 1 and Cytochrome P450 3A4 inhibitor N-[(2S,3R)-... 3 7
Pol polyprotein inhibitor Palinavir deriv. 13 family 1 0
Pol polyprotein and Cytochrome P450 3A4 inhibitor (2S)-4-(3a,6... 2 0
Renin inhibitor SureCN7300793 family 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00264225 CHEMBL52279 Bioactive (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[[(2S)-2-[(2-isoquinolin-5-yloxyacetyl)amino]-2-methylsulfanylacetyl]amino]-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide
CFAMM00264214 CHEMBL53355 Bioactive (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[[(2S)-2-[(2-isoquinolin-5-yloxyacetyl)amino]-2-methylsulfanylacetyl]amino]-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide
CFAMM00264216 DNC007479 Investigative Drug KNI-272
CFAMM00264223 DNC009332 Investigative Drug KNI-10527
CFAMM00264221 DNC009330 Investigative Drug KNI-10538
CFAMM00264220 DNC009331 Investigative Drug KNI-10526
CFAMM00264211 DNC007480 Investigative Drug KNI-227
CFAMM00264210 DNC007481 Investigative Drug KNI-10033

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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