CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2281
Family Name Plasmepsin-2 Inhibitor KNI-10314 Family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00264232 Functional Category Investigative Drug
Superfamily Plasmepsin-2 Binder Superfamily
Class Class 2410

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Nelfinavir Family 11 26
Plasmepsin-2 Inhibitor KNI-727 Family 3 37
Plasmepsin-2 Inhibitor KNI-10079 Family 19 8
Plasmepsin-2 Inhibitor KNI-10283 Family 24 0
Plasmepsin-2 Inhibitor KNI-10074 Family 1 0
Pol polyprotein inhibitor AHPBA 33 family 2 6
Pol polyprotein inhibitor AHPBA deriv. 33 family 13 0
Pol polyprotein inhibitor (2S)-N-[(2S,3R,4R)-3-hydroxy-5-[[(2R... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00264227 CHEMBL411608 Bioactive (4R)-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-3-[(2S,3S)-2-hydroxy-3-[[(2R)-2-[[2-(4-hydroxyphenyl)acetyl]amino]-3-methylsulfanylpropanoyl]amino]-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide
CFAMM00264235 DNC007482 Investigative Drug KNI-10315
CFAMM00264234 DNC007483 Investigative Drug KNI-10316
CFAMM00264233 DNC007486 Investigative Drug KNI-10341
CFAMM00264232 DNC007484 Investigative Drug KNI-10314
CFAMM00264231 DNC007485 Investigative Drug KNI-10342

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26855 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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