CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2286
Family Name Coagulation factor X and Neutrophil elastase Inhibitor ZK-814048 Family
No. of Seeds 51 No. of Other Members 17
Family Centroid CFAMM00264438 Functional Category Investigative Drug
Superfamily Coagulation factor X and Neutrophil elastase Inhibitor ZK-814048 Superfamily
Class Class 6

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Family 15 81
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
Metabotropic glutamate receptor 5 and Cytochrome P450 3A4 liga... 3 7
Coagulation factor X inhibitor 5-chloro-N-(5-chloropyridin-2-y... 1 0
Metabotropic glutamate receptor 5 ligand 2-oxo-N-pyridin-2-yl-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00264459 CHEMBL450012 Bioactive SureCN6592319
CFAMM00264452 CHEMBL226826 Bioactive SureCN6590330
CFAMM00264465 CHEMBL227195 Bioactive SureCN6591150
CFAMM00264479 CHEMBL226615 Bioactive SureCN6592212
CFAMM00264445 CHEMBL226931 Bioactive SureCN7699478
CFAMM00264431 CHEMBL376791 Bioactive SureCN6596704
CFAMM00264471 CHEMBL389638 Bioactive SureCN6588059
CFAMM00264486 CHEMBL389210 Bioactive Thiophene-Anthranilamide, 17p
CFAMM00264501 CHEMBL227249 Bioactive SureCN6592030
CFAMM00264451 CHEMBL226827 Bioactive SureCN6587514
CFAMM00264478 CHEMBL226616 Bioactive AGN-PC-0150KF
CFAMM00264494 CHEMBL390056 Bioactive AGN-PC-0150GH
CFAMM00264430 CHEMBL226668 Bioactive SureCN6594426
CFAMM00264444 CHEMBL425311 Bioactive SureCN6590572
CFAMM00264485 CHEMBL226879 Bioactive SureCN6591896
CFAMM00264437 CHEMBL441880 Bioactive SureCN6590042
CFAMM00264500 CHEMBL227248 Bioactive SureCN6591633
CFAMM00264450 CHEMBL226825 Bioactive SureCN6591301
CFAMM00264463 CHEMBL227197 Bioactive SureCN6590680
CFAMM00264476 CHEMBL227359 Bioactive AGN-PC-0150CU
CFAMM00264493 CHEMBL227308 Bioactive AGN-PC-0150CR
CFAMM00264429 CHEMBL226669 Bioactive AC1L9KKM
CFAMM00264443 CHEMBL227146 Bioactive SureCN6590267
CFAMM00264456 CHEMBL375264 Bioactive SureCN6592813
CFAMM00264484 CHEMBL226564 Bioactive SureCN6589645
CFAMM00264499 CHEMBL227360 Bioactive AGN-PC-0150GC
CFAMM00264462 CHEMBL227196 Bioactive SureCN6592005
CFAMM00264449 CHEMBL427276 Bioactive SureCN6591486
CFAMM00264475 CHEMBL226776 Bioactive SureCN6589738
CFAMM00264491 CHEMBL437546 Bioactive SureCN6591870
CFAMM00264455 CHEMBL227250 Bioactive SureCN6593086
CFAMM00264468 CHEMBL227145 Bioactive SureCN6593296
CFAMM00264483 CHEMBL390969 Bioactive SureCN6591692
CFAMM00264498 CHEMBL227307 Bioactive SureCN6590139
CFAMM00264461 CHEMBL375263 Bioactive SureCN6589922
CFAMM00264490 CHEMBL226721 Bioactive SureCN6590173
CFAMM00264441 CHEMBL226722 Bioactive SureCN6590414
CFAMM00264454 CHEMBL387656 Bioactive AGN-PC-046RAW
CFAMM00264467 CHEMBL387857 Bioactive SureCN6591195
CFAMM00264434 CHEMBL227223 Bioactive SureCN6592025
CFAMM00264497 CHEMBL390055 Bioactive AGN-PC-0150GE
CFAMM00264460 CHEMBL449703 Bioactive SureCN6591401
CFAMM00264473 CHEMBL226775 Bioactive SureCN6591789
CFAMM00264489 CHEMBL449702 Bioactive SureCN6590181
CFAMM00264453 CHEMBL376790 Bioactive SureCN6592257
CFAMM00264466 CHEMBL387856 Bioactive AGN-PC-0150KH
CFAMM00264480 CHEMBL388142 Bioactive SureCN6593428
CFAMM00264432 CHEMBL227221 Bioactive SureCN6592059
CFAMM00264438 DNC007525 Investigative Drug ZK-814048
CFAMM00264436 DNC007527 Investigative Drug ZK-813039
CFAMM00264435 DNC007526 Investigative Drug ZK-810388

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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