CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2296
Family Name Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor RTI-219 Family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00264627 Functional Category Investigative Drug
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor RTI-219 Superfamily
Class Class 2415

Cousin Family NamesSeedsMembers
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 16
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Histamine H1 receptor and Cytochrome P450 2D6 ligand 2-[3-[(1R... 1 10
D(4) dopamine receptor ligand SureCN8706945 family 4 10
Sodium-dependent serotonin transporter and D(4) dopamine recep... 2 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00264623 CHEMBL317111 Bioactive 2-[(1R,4S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-4-yl]-5-phenyl-1,3-thiazole
CFAMM00264622 CHEMBL390743 Bioactive 2-[(1S,3S,4S,5R)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-4-yl]-5-(4-fluorophenyl)-1,3-thiazole
CFAMM00264627 DNC007550 Investigative Drug RTI-219

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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