CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2301
Family Name Serine/threonine-protein kinase Chk1 Inhibitor BIS-IMIDE A Family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00264831 Functional Category Investigative Drug
Superfamily Poly [ADP-ribose] polymerase 1 and Serine/threonine-protein kinase Chk1 Binder Superfamily 2
Class Class 929

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline ... 4 151
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... 4 36
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Growth hormone receptor Ligand EP-51216 Family 34 390
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Cyclin-dependent kinase 5 Inhibitor 9-nitropaullone Family 2 13
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 16 0
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Platelet-derived growth factor receptor alpha and Platelet-der... 3 3
Kinesin-like protein KIF11 Inhibitor 9h-carbazole-2-carbaldehy... 1 3
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Vascular endothelial growth factor receptor 2 and Receptor-typ... 7 4
MAP kinase-activated protein kinase 2 and Mitogen-activated pr... 5 2
Thyroid hormone receptor beta and Microtubule-associated prote... 1 8
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 3
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
High affinity nerve growth factor receptor and BDNF/NT-3 growt... 4 3
Vascular endothelial growth factor receptor 2 and Angiopoietin... 14 0
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
High affinity nerve growth factor receptor ligand CHEMBL254555... 2 2
Protein kinase C alpha type and Protein kinase C delta type in... 2 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
Sodium-dependent serotonin transporter and D(2) dopamine recep... 1 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0
Mitogen-activated protein kinase kinase kinase 11 and Mitogen-... 1 1
Kinesin-like protein KIF11 inhibitor 9-(trifluoromethyl)-1,2,4... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00264831 DNC007574 Investigative Drug BIS-IMIDE A

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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