CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2328
Family Name Delta-type opioid receptor and Kappa-type opioid receptor Ligand N-(17-methylmorphinan-3-yl)-n'-phenylurea Family
No. of Seeds 7 No. of Other Members 13
Family Centroid CFAMM00265509 Functional Category Investigative Drug
Superfamily Kappa-type opioid receptor and Delta-type opioid receptor Binder Superfamily 3
Class Class 2121

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
D(2) dopamine receptor Ligand Nomifensine Family 6 100
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Urokinase-type plasminogen activator Inhibitor 6-(n-phenylcarb... 2 11
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 8 32
Androgen receptor Ligand YM-175735 Family 30 129
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Cannabinoid receptor 1 Ligand 1-[bis(4-iodophenyl)methyl]-3-(4... 4 13
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Dipeptidyl peptidase 4 Inhibitor (3s,4r)-3-butyl-1-phenylpiper... 2 40
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Tyrosinase Inhibitor 1-hydroxy-3-(4-(trifluoromethyl)phenyl)ur... 2 3
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 5 5
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 8
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 7 18
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Melanin-concentrating hormone receptor 1 ligand 3-(3-bromophen... 4 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,3,4-trifluorop... 2 2
Follicle-stimulating hormone receptor ligand AGN-PC-005HER family 5 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Sigma non-opioid intracellular receptor 1 ligand 1-[4-[1-adama... 4 23
Testosterone 17-beta-dehydrogenase 3 inhibitor SureCN4802053 f... 2 2
Melanin-concentrating hormone receptor 1 ligand SureCN14101999... 3 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(3,5... 2 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 4
C-C chemokine receptor type 3 ligand AGN-PC-073RIP family 2 4
C-C chemokine receptor type 5 ligand AC1L9YPM family 3 6
Transient receptor potential cation channel subfamily V member... 1 1
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRYI family 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 3 5
Melanin-concentrating hormone receptor 1 and Alpha-1A adrenerg... 1 0
C-X-C chemokine receptor type 3 ligand 3-[3,5-bis(trifluoromet... 3 5
Sterol O-acyltransferase 1 inhibitor SureCN7565101 family 2 10
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9352718 f... 2 3
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 1 3
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 2 0
Extracellular calcium-sensing receptor ligand 478963-46-1 family 2 2
NP (1r,5r)-n-(naphthalen-1-yl)-8-oxo-4,5,6,8-tetrahydro-1h-1,5... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00265505 DNC007679 Investigative Drug MCL-448
CFAMM00265504 DNC007678 Investigative Drug MCL-447
CFAMM00265510 DNC010086 Investigative Drug N-(4-Iodophenyl)-N'-(17-methylmorphinan-3-yl)urea
CFAMM00265503 DNC007677 Investigative Drug MCL-446
CFAMM00265509 DNC010085 Investigative Drug N-(17-Methylmorphinan-3-yl)-N'-phenylurea
CFAMM00265502 DNC007676 Investigative Drug MCL-445

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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