CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2337
Family Name Delta-type opioid receptor and Kappa-type opioid receptor Ligand 1-benzhydryl-4-(4-bromophenyl)piperidin-4-ol Family
No. of Seeds 11 No. of Other Members 3
Family Centroid CFAMM00265879 Functional Category Investigative Drug
Superfamily Delta-type opioid receptor and Kappa-type opioid receptor Ligand 1-benzhydryl-4-(4-bromophenyl)piperidin-4-ol Superfamily
Class Class 2427

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Histamine H1 receptor Ligand Terfenadine Family 3 50
Alpha adrenergic receptor Ligand Pseudoephedrine Family 4 96
Opioid receptor ligand opiate Levorphanol Family 18 537
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Histamine H1 receptor Ligand Chlophedianol Family 4 46
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Mu-type opioid receptor ligand opiate Methadyl Acetate Family 5 9
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Adenosine receptor A3 and D(2) dopamine receptor Ligand (+)-bu... 5 14
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Cytochrome P450 2D6 Inhibitor Bs 7840 Family 4 9
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Potassium voltage-gated channel subfamily H member 2 Ligand [1... 2 23
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Melanocortin receptor 4 and Melanocortin receptor 3 ligand Sur... 6 53
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 29
Sigma non-opioid intracellular receptor 1 ligand (1R)-1'-benzy... 7 27
Sigma non-opioid intracellular receptor 1 ligand 2-[(3R)-1'-(c... 2 0
Vesicular acetylcholine transporter inhibitor BENZOVESAMICOL f... 7 4
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 1 1
Histamine H3 receptor ligand 1-[[4-[4-[(1R)-4-methoxy-1-[(2S)-... 2 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 6 3
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 1
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 3 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 12
Sodium-dependent dopamine transporter and Sigma non-opioid int... 3 10
Vesicular acetylcholine transporter inhibitor (1R,2R)-2-spiro[... 3 2
Squalene synthase inhibitor 3-[2-(4-phenylphenyl)ethynyl]-1-az... 2 1
C-C chemokine receptor type 5 ligand AC1LAKN8 family 4 5
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Sigma non-opioid intracellular receptor 1 and Vesicular acetyl... 1 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand 8-[(2-c... 2 2
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-0793IB... 2 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 1
C-C chemokine receptor type 1 ligand SureCN9108653 family 2 5
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 7
D(1A) dopamine receptor and D(3) dopamine receptor ligand (2S,... 5 5
Membrane primary amine oxidase and Amine oxidase [flavin-conta... 2 0
Voltage-dependent N-type calcium channel subunit alpha-1B and ... 1 3
Putative NP ZINC55525127 Family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00265885 CHEMBL233536 Bioactive AGN-PC-0768OC
CFAMM00265882 CHEMBL233956 Bioactive 4-[2-(aminomethyl)phenyl]-1-[bis(2-bromophenyl)methyl]piperidin-4-ol
CFAMM00265879 DNC007729 Investigative Drug 1-benzhydryl-4-(4-bromophenyl)piperidin-4-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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