CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2339
Family Name Nitric oxide synthase, brain and Nitric oxide synthase, endothelial Inhibitor 1-(2-amino-benzothiazol-6-yl)-2-ethyl-isothiourea Family
No. of Seeds 2 No. of Other Members 11
Family Centroid CFAMM00265902 Functional Category Investigative Drug
Superfamily Nitric oxide synthase, brain and Nitric oxide synthase, endothelial Inhibitor 1-(2-amino-benzothiazol-6-yl)-2-ethyl-isothiourea Superfamily
Class Class 2148

Cousin Family NamesSeedsMembers
AP endonuclease APE1 Inhibitor 1,3-bis(1,3-benzothiazol-2-ylth... 1 12
Prothrombin Inhibitor Benzothiazole Family 1 29
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-amin... 5 24
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
C-C chemokine receptor type 4 Ligand 4-tert-butyl-n-o-tolylthi... 4 7
Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethy... 2 19
Neuropeptide S receptor and Niemann-Pick C1 protein ligand CHE... 1 1
Microtubule-associated protein tau inhibitor 4-[(6-iodo-1,3-be... 1 1
Microtubule-associated protein tau inhibitor Toluidine Blue O ... 2 0
(E)-2-(1,3-benzothiazol-2-yl)-3-thiophen-2-ylprop-2-enenitrile... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00265902 DNC007735 Investigative Drug 1-(2-amino-benzothiazol-6-yl)-2-ethyl-isothiourea
CFAMM00265901 DNC007736 Investigative Drug 1-(2-amino-benzothiazol-5-yl)-2-ethyl-isothiourea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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