CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2347
Family Name Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,1-dimethyl-heptyl)-2'-methoxy-biphenyl-2-ol Family
No. of Seeds 3 No. of Other Members 31
Family Centroid CFAMM00266132 Functional Category Investigative Drug
Superfamily Androgen receptor and Cannabinoid receptor 2 Binder Superfamily
Class Class 426

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Cannabinoid receptor 1 Ligand Marinol Family 32 454
Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor ligand steroid Estradiol Family 18 147
Oestrogen receptor ligand Dienestrol Family 35 440
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
Salicin family 5 629
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
Translocator protein Inhibitor Dextofisopam Family 3 250
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
TS-071 family 8 36
Bile acid receptor Ligand SR-45023A (apomine) Family 3 34
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 2 22
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 5 13
Arachidonate 15-lipoxygenase Inhibitor Hydrohalisulfate 1 Family 6 6
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Tubulin beta chain Inhibitor Combretastatin Family 3 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Androgen receptor Ligand 4-(m-tolyloxy)-2-(trifluoromethyl)ben... 7 65
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 5 8
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Androgen receptor Ligand 2'-hydroxy-3-methoxy-biphenyl-4-carbo... 2 13
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Indoleamine 2,3-dioxygenase 1 Inhibitor Naphthalene-1,4-diol F... 2 4
Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tol... 4 11
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Prostaglandin G/H synthase 1 Inhibitor 2-(2-methoxyphenyl)-1h-... 1 11
Tyrosinase Inhibitor 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-d... 4 2
Androgen receptor Ligand Palodesangren E Family 12 43
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand [(6aR... 1 0
Prelamin-A/C and Solute carrier organic anion transporter fami... 1 15
Cannabinoid receptor 1 ligand 6,6,9-trimethyl-3-(6-nitrohex-2-... 1 0
Vitamin D3 receptor ligand (3E,5E)-6-[3-[[3,4-bis(hydroxymethy... 2 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 14
Estrogen receptor beta and Estrogen receptor ligand SureCN4017... 3 5
Histone deacetylase 2 and Histone deacetylase 8 inhibitor AC1L... 2 2
Vitamin D3 receptor ligand (1R,3S,5Z)-5-[(2E)-2-[(3aS,7aR)-1-[... 1 2
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 2 7
Steroidogenic factor 1 and Nuclear receptor subfamily 5 group ... 1 1
Trace amine-associated receptor 1 ligand 4-[4-(2-AMINO-ETHYL)-... 1 0
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 6 6
Arachidonate 5-lipoxygenase inhibitor SureCN9727660 family 1 0
Arachidonate 5-lipoxygenase inhibitor SureCN9727677 family 1 2
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 2 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-04VJ4H family 1 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 1-[3,... 4 0
Tyrosine-protein phosphatase non-receptor type 1 and Tyrosine-... 2 1
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 17
Benzoxepines Metabolite Enokipodin A Family 1 0
Phenols and Derivatives Metabolite 2-(Ethoxymethyl)phenol Family 1 14
Benzene and Substituted Derivatives Metabolite 1,3,5-Trimethox... 2 17
NP (1r,2r,4s)-2-(2-methoxyphenyl)-1,3,3-trimethylbicyclo[2.2.1... 3 0
NP 4-(chloromethyl)-6-methoxy-2h-chromen-2-one Family 4 2
4-(9H-xanthen-9-yl)-9H-xanthene NP 9h,9'h-4,9'-bixanthene Family 1 0
Putative NP ZINC00526277 Family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00266132 DNC007762 Investigative Drug 4-(1,1-dimethyl-heptyl)-2'-methoxy-biphenyl-2-ol
CFAMM00266131 DNC007761 Investigative Drug 4-(1,1-dimethyl-heptyl)-3'-methoxy-biphenyl-2-ol
CFAMM00266123 DNC009128 Investigative Drug 2,6-di-tert-butyl-4-methoxyphenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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