CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2355
Family Name Cholinesterase Inhibitor 1-(10h-phenothiazin-10-yl)-2-phenylbutan-1-one Family
No. of Seeds 10 No. of Other Members 4
Family Centroid CFAMM00266400 Functional Category Investigative Drug
Superfamily Cholinesterase and Reverse transcriptase Binder Superfamily
Class Class 545

Cousin Family NamesSeedsMembers
Cholesteryl ester transfer protein Inhibitor Dalcetrapib Family 1 2
Cholinesterase Inhibitor (10h-phenothiazin-10-yl)(phenyl)metha... 6 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 2
Substance-P receptor ligand AGN-PC-073MZ3 family 2 0


External ID

Functional Category

Molecule Name

CFAMM00266405 DNC007781 Investigative Drug anthracen-10-yl(10H-phenothiazin-10-yl)methanone
CFAMM00266403 DNC007782 Investigative Drug naphthalen-2-yl(10H-phenothiazin-10-yl)methanone
CFAMM00266402 DNC007785 Investigative Drug 1-(10H-phenothiazin-10-yl)-4-phenylbutan-1-one
CFAMM00266410 DNC007790 Investigative Drug 1-(10H-phenothiazin-10-yl)-2-phenylethanone
CFAMM00266401 DNC007784 Investigative Drug 2-biphenyl-4-yl-1-phenothiazin-10-yl-ethanone
CFAMM00266409 DNC007783 Investigative Drug naphthalen-1-yl(10H-phenothiazin-10-yl)methanone
CFAMM00266400 DNC007787 Investigative Drug 1-(10H-phenothiazin-10-yl)-2-phenylbutan-1-one
CFAMM00266407 DNC007786 Investigative Drug 1-(10H-phenothiazin-10-yl)-3-phenylbutan-1-one
CFAMM00266399 DNC007789 Investigative Drug 1-(10H-phenothiazin-10-yl)-2-phenylpropan-1-one
CFAMM00266398 DNC007788 Investigative Drug 1-(10H-phenothiazin-10-yl)-3-phenylpropan-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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