CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2358
Family Name Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)quinolin-2(1h)-one Family
No. of Seeds 2 No. of Other Members 44
Family Centroid CFAMM00266558 Functional Category Investigative Drug with Natural Product
Superfamily Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)quinolin-2(1h)-one Superfamily
Class Class 2432

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Metabotropic glutamate receptor 5 Ligand 3-chloro-n-(4-methylt... 2 12
Transient receptor potential cation channel subfamily V member... 1 17
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Phosphoribosylaminoimidazolecarboxamide formyltransferase Inhi... 1 13
Muscarinic acetylcholine receptor M4 Ligand VU10007 Family 2 17
Peroxisome proliferator-activated receptor alpha and Peroxisom... 4 8
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 7-[4... 3 0
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 13 37
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-3-... 2 1
Amyloid beta A4 protein and Luciferin 4-monooxygenase inhibito... 11 46
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 8 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor th... 1 3
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor (3... 1 5
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Transient receptor potential cation channel subfamily V member... 22 3
Cathepsin K inhibitor N-(cyanomethyl)-5,5-difluoro-2-[2-methyl... 1 0
Gamma-aminobutyric acid receptor subunit alpha-2 and Gamma-ami... 6 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 2
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 1 4
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 1 17
Proto-oncogene tyrosine-protein kinase LCK and Tyrosine-protei... 3 9
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00266482 CHEMBL391906 Bioactive SureCN5464869
CFAMM00266558 DNC007798 Investigative Drug 3-(2-phenylthiazol-4-yl)quinolin-2(1H)-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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