CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID237
Family Name Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family
No. of Seeds 1 No. of Other Members 21
Family Centroid CFAMM00185244 Functional Category Investigative Drug with Natural Product
Superfamily Dihydroorotate dehydrogenase Inhibitor Brequinar Superfamily
Class Class 943

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Diacylglycerol O-acyltransferase 2 and Hydroxycarboxylic acid ... 4 45
Neuromedin-K receptor Ligand Talnetant Family 3 49
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Retinoic acid receptor alpha Ligand LG100268 Family 2 33
Tyrosine-protein phosphatase non-receptor type 1 Ligand 6-(oxa... 1 5
Fatty acid-binding protein, adipocyte Inhibitor 2-(3-methyl-in... 5 9
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Egl nine homolog 2 Inhibitor Pyridine-2,4-dicarboxylic Acid Fa... 2 21
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Isoqui... 1 6
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Metabotropic glutamate receptor 5 Ligand (3-(2-methylquinolin-... 3 6
Metabotropic glutamate receptor 5 Ligand 6-phenylethynyl-nicot... 2 26
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
NS5B protein inhibitor AC1NQMYG family 6 12
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 4 7
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
NS5B protein inhibitor AC1NQMYP family 5 0
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C9 liga... 2 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 3
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 5
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 1 1
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
ATP-sensitive inward rectifier potassium channel 11 ligand N-[... 1 1
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 3
Transmembrane prolyl 4-hydroxylase inhibitor 2,2'-Bipyridine-5... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00185244 DNC000435 Investigative Drug Cinchoninic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23197 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543