CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2370
Family Name Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B Inhibitor 7-(3-chlorobenzyloxy)-4-carboxaldehyde-coumarin Family
No. of Seeds 4 No. of Other Members 160
Family Centroid CFAMM00266888 Functional Category Investigative Drug with Natural Product
Superfamily Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B Inhibitor 7-(3-chlorobenzyloxy)-4-carboxaldehyde-coumarin Superfamily
Class Class 2438

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor alpha Ligand Fenofi... 3 127
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
Ipriflavone family 62 2480
Salicin family 5 629
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 2 22
Coagulation factor X and Prothrombin Inhibitor 3-chlorophenyl ... 2 12
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Prostaglandin D2 receptor 2 Ligand 2-(4-chloro-2-cyclohexylphe... 7 25
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Androgen receptor Ligand 2-methoxy-4-(o-tolyloxy)benzonitrile ... 5 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
NAD(P)H dehydrogenase [quinone] 1 Inhibitor Ethyl Bis(4-hydrox... 5 7
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Cytochrome P450 2D6 Inhibitor 4-methylaminomethyl-7-methoxycou... 3 80
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-c... 5 72
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Peroxisome proliferator-activated receptor alpha and Peroxisom... 4 28
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 32
Peroxisome proliferator-activated receptor alpha and Peroxisom... 7 6
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 3
Peroxisome proliferator-activated receptor alpha ligand AGN-PC... 5 2
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 0
Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial ... 3 5
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-[(4... 3 53
Free fatty acid receptor 1 ligand SureCN14018049 family 1 0
NAD(P)H dehydrogenase [quinone] 1 inhibitor AGN-PC-0AKS1I family 1 0
Multidrug resistance protein 1 inhibitor CHEMBL1 family 2 0
Aldose reductase inhibitor 2-(7-chloro-2-oxochromen-4-yl)aceti... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00266896 CHEMBL109018 Bioactive ZINC00453884
CFAMM00266807 CHEMBL1830817 Bioactive ethyl 7-[(3,4-dichlorophenyl)methoxy]-2-oxochromene-3-carboxylate
CFAMM00266888 DNC007834 Investigative Drug 7-(3-chlorobenzyloxy)-4-carboxaldehyde-coumarin

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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