CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2371
Family Name Thyroid hormone receptor alpha and Thyroid hormone receptor beta Ligand 1-(4-hexylphenyl)-3-morpholinopropan-1-one Family
No. of Seeds 4 No. of Other Members 10
Family Centroid CFAMM00266916 Functional Category Investigative Drug
Superfamily Thyroid hormone receptor alpha and Thyroid hormone receptor beta Ligand 1-(4-hexylphenyl)-3-morpholinopropan-1-one Superfamily
Class Class 2439

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Opioid receptor Ligand Methadone Family 3 39
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Bavisant family 9 65
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Sodium-dependent dopamine transporter and Sodium-dependent nor... 10 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Thyroid hormone receptor beta Ligand 1-(4-hexylphenyl)-3-(prop... 2 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Kappa-type opioid receptor ligand 6-[2-oxo-2-[(2S)-2-(pyrrolid... 6 4
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 3 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 2
Sigma non-opioid intracellular receptor 1 ligand N-Phprop-clph... 1 12
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2
Acetylcholinesterase inhibitor 5-benzoyl-2-[2-(1-benzylpiperid... 2 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Melanin-concentrating hormone receptor 1 ligand 1-(3-acetyl-1,... 8 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 9 0
Prolyl endopeptidase and Seprase inhibitor [(2R)-1-(4-oxo-4-ph... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 7 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 11 2
Histamine H3 receptor ligand AGN-PC-01WA6E family 10 1
5-hydroxytryptamine receptor 1A ligand [(7S,8R)-7-(dipropylami... 4 0
Lanosterol synthase and Cycloartenol synthase inhibitor (4-bro... 1 2
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-074TEL... 1 7
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 1 0
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00266915 CHEMBL555975 Bioactive AGN-PC-07C2BZ
CFAMM00266916 DNC007837 Investigative Drug 1-(4-hexylphenyl)-3-morpholinopropan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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