CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2374
Family Name Thyroid hormone receptor alpha and Thyroid hormone receptor beta Ligand (z)-4-(4-hexylphenylamino)-4-oxobut-2-enoic Acid Family
No. of Seeds 1 No. of Other Members 16
Family Centroid CFAMM00267043 Functional Category Investigative Drug
Superfamily Dihydroorotate dehydrogenase and Thyroid hormone receptor beta Binder Superfamily
Class Class 2370

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
Pan-DAC Inhibitor AR-42 Family 21 153
Proto-oncogene tyrosine-protein kinase Src Inhibitor ISO24 Family 3 9
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Transient receptor potential cation channel subfamily V member... 6 33
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Fatty-acid amide hydrolase 1 Inhibitor 1-biphenyl-4-ylmaleimid... 2 11
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Aldose reductase Inhibitor (4-methyl-2-oxo-2h-quinolin-1-yl)-a... 1 15
Tyrosinase Inhibitor S-2-(o-toluidino)-2-oxoethyl Carbamothioa... 1 1
DNA topoisomerase Inhibitor 6-p-tolylamino-1h-pyrimidine-2,4-d... 3 17
Mitogen-activated protein kinase 1 and M17 leucyl aminopeptida... 1 21
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 1 16
Integrin beta-1 and Integrin alpha-5 inhibitor (Z)-2-[1-[(4-am... 1 1
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 1 3
Lysophosphatidic acid receptor 2 and Lysophosphatidic acid rec... 1 0
Lysophosphatidic acid receptor 3 and Microtubule-associated pr... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00267043 DNC007844 Investigative Drug (Z)-4-(4-hexylphenylamino)-4-oxobut-2-enoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27429 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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