CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2385
Family Name 5-hydroxytryptamine receptor 2B and 5-hydroxytryptamine receptor 2C Ligand WAY-181187 Family
No. of Seeds 7 No. of Other Members 15
Family Centroid CFAMM00267202 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2B Binder Superfamily
Class Class 392

Cousin Family NamesSeedsMembers
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
5-hydroxytryptamine receptor 6 ligand 6-chloro-5-[1-(1-methylp... 9 0
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
Adenosine receptor A2a and Adenosine receptor A1 ligand [(2S)-... 2 0
5-hydroxytryptamine receptor 6 ligand 2-[(E)-[6-[(6-chloroimid... 10 3
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 3 1


External ID

Functional Category

Molecule Name

CFAMM00267195 CHEMBL367088 Bioactive AGN-PC-004ZAZ
CFAMM00267201 CHEMBL564371 Bioactive AGN-PC-07C6JB
CFAMM00267205 CHEMBL175940 Bioactive SureCN3153057
CFAMM00267198 CHEMBL558306 Bioactive 1-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfonylpyrrolo[3,2-b]pyridin-6-amine
CFAMM00267197 CHEMBL362628 Bioactive E-6801
CFAMM00267215 CHEMBL574404 Bioactive 2-[(E)-1-[1-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfonylindol-3-yl]ethylideneamino]guanidine
CFAMM00267202 DNC007865 Investigative Drug WAY-181187

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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