CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2393
Family Name NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-amino-2h-chromen-2-one Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00267437 Functional Category Investigative Drug with Natural Product
Superfamily NAD(P)H dehydrogenase [quinone] 1 and Peptidyl-prolyl cis-trans isomerase A Binder Superfamily
Class Class 1859

Cousin Family NamesSeedsMembers
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
D(4) dopamine receptor Ligand PD-165167 Family 2 96
DNA-dependent protein kinase catalytic subunit Inhibitor 4-mor... 7 54
DNA-dependent protein kinase catalytic subunit Inhibitor 6-chl... 2 9
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Amine oxidase [flavin-containing] B Inhibitor N-isobutyl-2-oxo... 4 8
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Cytochrome P450 2D6 Inhibitor 4-methylaminomethyl-7-methoxycou... 3 80
Estrogen receptor ligand 4-(dodecylamino)-3-[(2-methylphenyl)m... 1 2
Amine oxidase [flavin-containing] B inhibitor benzyl N-(2-oxoc... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00267432 DNC010072 Investigative Drug 6-(aminomethyl)-2H-chromen-2-one
CFAMM00267437 DNC007891 Investigative Drug 4-amino-2H-chromen-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44593 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543