CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2394
Family Name Adenosine receptor A3 Ligand 2-aminoquinazoline-4-carboxyanilide Family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00267443 Functional Category Investigative Drug
Superfamily Adenosine receptor A3 and 5-hydroxytryptamine receptor 1A Binder Superfamily
Class Class 824

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Prothrombin Inhibitor Dabigatran Family 7 182
Mitogen-activated protein kinase 12 Inhibitor VX-702 Family 3 49
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
Poly [ADP-ribose] polymerase 1 Inhibitor 2-ethylquinoline-8-ca... 3 4
Cyclin-dependent kinase 2 and Mitogen-activated protein kinase... 7 30
Metabotropic glutamate receptor 5 Ligand 3-chloro-n-(6-chlorop... 2 5
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(6-methylpy... 4 3
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Adenosine receptor A1 Ligand N-(4,6-diphenylpyrimidin-2-yl)ben... 4 8
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2,6... 22 18
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Metabotropic glutamate receptor 5 Ligand N-(1,3-diphenyl-1h-py... 6 37
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-amin... 10 48
Substance-P receptor ligand (3R,4S)-N-[[3,5-bis(trifluoromethy... 3 7
Neuronal acetylcholine receptor subunit alpha-7 ligand 2-(4-cy... 1 0
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Cell division cycle 7-related protein kinase inhibitor pyrrolo... 4 10
5-hydroxytryptamine receptor 1A ligand AGN-PC-03ZB72 family 10 8
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 19
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Dihydrofolate reductase inhibitor 1-[3-(2,4-diaminoquinazolin-... 2 4
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
Hepatocyte growth factor receptor ligand 5-[(6-phenyl-[1,2,4]t... 6 2
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Substance-P receptor ligand 2-[3,5-bis(trifluoromethyl)phenyl]... 3 1
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 2
G-protein coupled bile acid receptor 1 ligand 2-(ethylamino)-6... 5 4
C-C chemokine receptor type 5 ligand N-[3-[4-[3-cyclohexyl-5-(... 5 4
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... 11 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Collagenase 3 inhibitor MMP-13 Inhibitor family 1 1
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... 6 0
Dihydrofolate reductase inhibitor N-(2,4-diamino-5-methylquina... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00267443 DNC007900 Investigative Drug 2-aminoquinazoline-4-carboxyanilide
CFAMM00267441 DNC007897 Investigative Drug 2-acetylaminoquinazoline-4-carboxyanilide
CFAMM00267440 DNC007896 Investigative Drug 2-benzoylaminoquinazoline-4-carboxyanilide
CFAMM00267439 DNC007899 Investigative Drug 2-aminoquinazoline-4-carboxy-(4-bromophenyl)amide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26179 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543