CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2418
Family Name Chymase Inhibitor Chymostatin Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00267792 Functional Category Investigative Drug
Superfamily Chymase and Nociceptin receptor Binder Superfamily
Class Class 608

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Prothrombin Inhibitor Efegatran Family 9 47
Neuromedin-K receptor Ligand Senktide Family 15 22
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Disintegrin and metalloproteinase domain-containing protein 17... 8 7
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Endothelin-converting enzyme 1 Inhibitor PO3 2-leu-nal-o-3k Fa... 3 26
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Trypsin Inhibitor P1 Argininal Derivative Family 13 36
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-3-[... 13 17
Prothrombin inhibitor SureCN7341151 family 6 7
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(1R,5S,11S,1... 8 2
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R,6S,12S)-6... 7 0
Type-2 angiotensin II receptor ligand SureCN3515167 family 2 0
Prothrombin inhibitor 2-[(3R)-3-amino-3-benzyl-2-oxopiperidin-... 3 0
Histone deacetylase 1 and Histone deacetylase 8 inhibitor meth... 1 3
Angiotensin-converting enzyme inhibitor SureCN7263641 family 2 11
Neurotensin receptor type 2 and Neurotensin receptor type 1 li... 1 1
Beta-secretase 1 inhibitor (2R)-4-amino-2-[[(2S)-2-[[(2S)-2-[[... 2 1
Prothrombin and Trypsin-1 inhibitor 4-[2-[1-[(2R)-2-amino-3-ph... 1 0
Bifunctional epoxide hydrolase 2 inhibitor (2S)-3-(3a,7a-dihyd... 1 0
Bcl-2-like protein 1 inhibitor CHEMBL501005 family 2 2
Neuraminidase inhibitor AC1NQT84 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00267794 CHEMBL247767 Bioactive Chymostatin
CFAMM00267792 DNC007963 Investigative Drug CHYMOSTATIN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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