CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2426
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(3-methoxyphenyl)-2-(phenylsulfonyl)ethanone Family
No. of Seeds 2 No. of Other Members 16
Family Centroid CFAMM00267916 Functional Category Investigative Drug
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(3-methoxyphenyl)-2-(phenylsulfonyl)ethanone Superfamily
Class Class 2460

Cousin Family NamesSeedsMembers
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Collagenase 3 and Interstitial collagenase Inhibitor 3-(4-meth... 12 76
Cysteinyl leukotriene receptor 1 ligand 4-[(E)-1-carboxy-6-[4-... 2 9
Prostaglandin G/H synthase 2 inhibitor [4-[3-(4-methylsulfonyl... 3 10
72 kDa type IV collagenase and Stromelysin-1 inhibitor 3-cyclo... 5 0
Amine oxidase [flavin-containing] A inhibitor BW 1370U87 family 3 29
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 2
Histone deacetylase 6 and Histone deacetylase 1 inhibitor AGN-... 1 1
Seed linoleate 13S-lipoxygenase-1 and Prostaglandin G/H syntha... 1 1


External ID

Functional Category

Molecule Name

CFAMM00267913 DNC007979 Investigative Drug 1-(4-methoxyphenyl)-2-(phenylsulfonyl)ethanone
CFAMM00267916 DNC007976 Investigative Drug 1-(3-methoxyphenyl)-2-(phenylsulfonyl)ethanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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