CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2427
Family Name Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta Ligand 2-benzyl-4,5,6,7-tetrachloroisoindoline-1,3-dione Family
No. of Seeds 2 No. of Other Members 23
Family Centroid CFAMM00267930 Functional Category Investigative Drug
Superfamily Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta Ligand 2-benzyl-4,5,6,7-tetrachloroisoindoline-1,3-dione Superfamily
Class Class 2461

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Thalidomide Family 3 50
Neuromedin-K receptor Ligand Osanetant Family 38 192
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Tumor necrosis factor Inhibitor Talactoferrin Alfa Family 26 131
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Acetylcholinesterase inhibitor 5-benzoyl-2-[2-(1-benzylpiperid... 2 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 2
Prelamin-A/C and Ras-related protein Rab-9A inhibitor CHEMBL15... 1 7
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075C6K ... 3 22
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Carbonic anhydrase 7 and Carbonic anhydrase 2 inhibitor 4-(4,5... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 4
Histamine H3 receptor ligand AGN-PC-01WA6E family 10 1
5-hydroxytryptamine receptor 1A and Alpha-2B adrenergic recept... 2 2
Aldose reductase inhibitor SureCN8804611 family 2 0
Reverse transcriptase/RNaseH inhibitor (R)-(+)9B-(3-METHYL)PHE... 5 24
Isoindoles and Derivatives Metabolite Folpet Family 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00267931 DNC007985 Investigative Drug 5-chloro-2-(4-phenylbutyl)isoindoline-1,3-dione
CFAMM00267930 DNC007984 Investigative Drug 2-benzyl-4,5,6,7-tetrachloroisoindoline-1,3-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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