CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2431
Family Name Prostaglandin D2 receptor 2 Ligand 2-(4-cyano-2-cyclohexylphenoxy)acetic Acid Family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00268036 Functional Category Investigative Drug
Superfamily Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Superfamily
Class Class 614

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Doxepin Family 8 89
Lipoprotein lipase Inhibitor Clofibrate Family 3 28
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Peroxisome proliferator-activated receptor alpha Ligand Ciprof... 1 5
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 2 14
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Prostaglandin D2 receptor 2 Ligand 2-(4-bromo-2-tert-butylphen... 3 4
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Prostaglandin D2 receptor 2 Ligand 2-(4-chloro-2-cyclohexylphe... 7 25
Androgen receptor Ligand 4-(m-tolyloxy)-2-(trifluoromethyl)ben... 7 65
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Androgen receptor Ligand Palodesangren E Family 12 43
Prelamin-A/C and Solute carrier organic anion transporter fami... 1 15
Prostaglandin D2 receptor 2 and Chemoattractant receptor-homol... 4 37
Prostaglandin D2 receptor 2 ligand 2-[4-chloro-2-[2-(5-ethylsu... 26 8
Prostaglandin D2 receptor 2 ligand 2-[4-chloro-2-[2-[5-(diethy... 14 0
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R)... 1 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand (6aR,... 1 3
Prostaglandin D2 receptor 2 ligand 2-[2-[2-(2-chlorophenyl)eth... 1 0
Free fatty acid receptor 1 ligand 3-[4-[2-[2-(cyanomethoxy)phe... 1 2
ahydropyrano[3,2-c]chromene NP ZINC04023039 Family 16 2


External ID

Functional Category

Molecule Name

CFAMM00268041 CHEMBL1778635 Bioactive AGN-PC-0A9TLT
CFAMM00268040 CHEMBL1778636 Bioactive AGN-PC-008EYC
CFAMM00268039 CHEMBL1778656 Bioactive (2R)-2-[2-(3-cyanophenyl)-4-(trifluoromethyl)phenoxy]propanoic acid
CFAMM00268038 CHEMBL1778628 Bioactive AGN-PC-0A9UXA
CFAMM00268037 CHEMBL1777822 Bioactive AGN-PC-0A9U5P
CFAMM00268036 DNC008000 Investigative Drug 2-(4-cyano-2-cyclohexylphenoxy)acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



71557 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543