CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2432
Family Name Beta-3 adrenergic receptor Ligand BMS-196085 Family
No. of Seeds 18 No. of Other Members 72
Family Centroid CFAMM00268070 Functional Category Investigative Drug
Superfamily Beta-3 adrenergic receptor Ligand BMS-196085 Superfamily
Class Class 880

Cousin Family NamesSeedsMembers
Beta-2 adrenergic receptor Ligand Formoterol Family 16 63
Potassium voltage-gated channel subfamily H member 2 Ligand Do... 5 30
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Beta-2 adrenergic receptor Ligand Procaterol Family 7 42
Beta-2 adrenergic receptor Ligand Olodaterol Family 16 27
D(2) dopamine receptor Ligand Ar-c68397aa Family 18 81
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 5 16
Beta-secretase 1 and Cathepsin D inhibitor 3ixj family 10 21
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 5
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 1
Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN5224847 ... 3 24
Beta-2 adrenergic receptor ligand SureCN5041910 family 12 1
Beta-2 adrenergic receptor ligand SureCN12305711 family 6 3
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 3
Beta-3 adrenergic receptor ligand N-[5-[2-[[1-[4-[(Z)-(2-amino... 5 2
Beta-2 adrenergic receptor ligand 4-[2-[2-[4-[[2-(2,5-dimethox... 1 1
Beta-3 adrenergic receptor ligand N-[5-[(3R)-4-[[(1R)-1-(3,4-d... 1 0
Beta-secretase 1 and Beta-secretase 2 inhibitor 3-(1,1-dioxoth... 6 2
Beta-3 adrenergic receptor ligand (2S)-N-(4-chlorophenyl)-2-[[... 1 8
Beta-secretase 1 inhibitor N-[(2S,3R)-1-(3,5-difluorophenyl)-3... 5 5
Beta-secretase 1 inhibitor 1-N-[(2S,3R)-1-(3,5-difluorophenyl)... 8 7
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 1 0
Cathepsin E and Cathepsin D inhibitor SureCN2529506 family 2 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0
Pol polyprotein inhibitor AC1LA3AU family 1 0
D(3) dopamine receptor ligand SureCN2078708 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00268051 CHEMBL401135 Bioactive N-[5-[(3R)-4-[[(1R)-1-[4-(difluoromethoxy)phenyl]-2-phenylethyl]amino]-3-hydroxybutanoyl]-2-hydroxyphenyl]methanesulfonamide
CFAMM00268123 CHEMBL1243407 Bioactive ZINTEROL
CFAMM00268090 CHEMBL437578 Bioactive SureCN7672280
CFAMM00268116 CHEMBL1773264 Bioactive SureCN4160120
CFAMM00268102 CHEMBL398557 Bioactive N-[5-[(2S)-3-[[(1S)-1-(3,4-dimethoxyphenyl)-2-phenylethyl]amino]-2-hydroxypropyl]-2-hydroxyphenyl]methanesulfonamide
CFAMM00268108 CHEMBL400947 Bioactive SureCN7674878
CFAMM00268101 CHEMBL399329 Bioactive SureCN7670221
CFAMM00268042 CHEMBL60116 Bioactive UNII-WS7S13Q9RH
CFAMM00268081 CHEMBL250191 Bioactive N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[2-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]methanesulfonamide
CFAMM00268107 CHEMBL400067 Bioactive N-[5-[(2R)-3-[[(1S)-1-(3,4-dimethoxyphenyl)-3-phenylpropyl]amino]-2-hydroxypropyl]-2-hydroxyphenyl]methanesulfonamide
CFAMM00268126 CHEMBL105758 Bioactive N-[5-[(1R)-2-[[(1R)-1-[4-(difluoromethoxy)naphthalen-1-yl]-2-phenylethyl]amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
CFAMM00268106 CHEMBL1243256 Bioactive SureCN5037158
CFAMM00268119 CHEMBL1773262 Bioactive N-[5-[(1R)-2-[2-[3-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-hydroxyphenyl]ethylamino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
CFAMM00268086 CHEMBL321518 Bioactive SureCN7039407
CFAMM00268079 CHEMBL250755 Bioactive SureCN7668969
CFAMM00268046 CHEMBL317648 Bioactive N-[5-[(1R)-2-[[(2R)-2-[4-(difluoromethoxy)phenyl]-1-phenylpropan-2-yl]amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
CFAMM00268117 CHEMBL1773266 Bioactive SureCN4154414
CFAMM00268070 DNC008009 Investigative Drug BMS-196085

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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