CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2440
Family Name Cruzipain Inhibitor K-777 Family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00268276 Functional Category Investigative Drug
Superfamily C-C chemokine receptor type 5 Ligand AZD5672 Superfamily
Class Class 905

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 5 Ligand AZD5672 Family 25 70
Renin Inhibitor CP-80794 Family 16 112
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Cathepsin S and Cathepsin L1 inhibitor N-[1-(morpholin-4-ylcar... 1 1
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 4 2
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 15 0
Coagulation factor X inhibitor ethyl 2-[[(3S)-3-[[2-[[(2R)-2-(... 4 0
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00268282 CHEMBL222649 Bioactive LHVS
CFAMM00268283 DNC009400 Investigative Drug GNF-PF-5434
CFAMM00268276 DNC008060 Investigative Drug K-777

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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