CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2455
Family Name Mitogen-activated protein kinase 12 and Mitogen-activated protein kinase 1 Inhibitor KN-62 Family
No. of Seeds 7 No. of Other Members 25
Family Centroid CFAMM00268467 Functional Category Investigative Drug
Superfamily Mitogen-activated protein kinase 12 and Mitogen-activated protein kinase 1 Inhibitor KN-62 Superfamily
Class Class 2465

Cousin Family NamesSeedsMembers
Oxytocin receptor and Vasopressin V1a receptor ligand 4-methox... 9 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00268459 CHEMBL28262 Bioactive [4-[(2S)-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-[4-(2-methylphenyl)piperazin-1-yl]-3-oxopropyl]phenyl] isoquinoline-5-sulfonate
CFAMM00268451 CHEMBL338578 Bioactive AGN-PC-02K7WE
CFAMM00268456 CHEMBL434773 Bioactive [4-[(2S)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-oxopropyl]phenyl] isoquinoline-5-sulfonate
CFAMM00268462 CHEMBL282807 Bioactive [4-[(2S)-3-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-oxopropyl]phenyl] isoquinoline-5-sulfonate
CFAMM00268448 CHEMBL282173 Bioactive [4-[(2S)-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-[4-(4-nitrophenyl)piperazin-1-yl]-3-oxopropyl]phenyl] isoquinoline-5-sulfonate
CFAMM00268475 CHEMBL282552 Bioactive [4-[(2S)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-(isoquinolin-5-ylsulfonylamino)-3-oxopropyl]phenyl] isoquinoline-5-sulfonate
CFAMM00268467 DNC008115 Investigative Drug KN-62

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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