CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2463
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2C Ligand 5-chloro-4-ethyl-3,4-dihydroquinazolin-2-amine Family
No. of Seeds 4 No. of Other Members 18
Family Centroid CFAMM00268817 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 5A Binder Superfamily
Class Class 2027

Cousin Family NamesSeedsMembers
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor Anag... 2 8
Peptide deformylase, mitochondrial Inhibitor Proguanil Family 8 46
5-hydroxytryptamine receptor 5A Ligand N,4-dimethyl-3,4-dihydr... 8 51
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 0
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 0
Sigma non-opioid intracellular receptor 1 and Glutamate recept... 1 10
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 3
Dihydrofolate reductase inhibitor AC1MBSH5 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00268815 DNC008153 Investigative Drug 5-chloro-4-methyl-3,4-dihydroquinazolin-2-amine
CFAMM00268817 DNC008151 Investigative Drug 5-chloro-4-ethyl-3,4-dihydroquinazolin-2-amine
CFAMM00268804 DNC008144 Investigative Drug 5-chloro-3,4-dihydroquinazolin-2-amine
CFAMM00268816 DNC008150 Investigative Drug 8-chloro-3,4-dihydroquinazolin-2-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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