CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2470
Family Name NF-kappa-B Inhibitor 5-bromo-n-(quinolin-8-yl)thiophene-2-sulfonamide Family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00268918 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 6 Ligand SB-742457 Superfamily
Class Class 8

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Prostaglandin E2 receptor EP3 subtype Ligand DG041 Family 9 16
5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
NF-kappa-B Inhibitor 9-chloro-5h-6-thia-4,5-diaza-chrysene 6,6... 3 27
NF-kappa-B Inhibitor 2-nitro-n-(quinolin-8-yl)benzenesulfonami... 2 3
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 ligand SureCN3147604 family 7 6
5-hydroxytryptamine receptor 6 ligand 1-(4-chlorophenyl)sulfon... 8 4
5-hydroxytryptamine receptor 6 ligand 1-(5-bromothiophen-2-yl)... 4 0
5-hydroxytryptamine receptor 6 ligand 3,4-dichloro-N-[3-[[(2R)... 5 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 0
Prostaglandin E2 receptor EP3 subtype ligand N-(4,5-dichloroth... 3 0


External ID

Functional Category

Molecule Name

CFAMM00268919 DNC008180 Investigative Drug 5-chloro-N-(quinolin-8-yl)thiophene-2-sulfonamide
CFAMM00268918 DNC008179 Investigative Drug 5-bromo-N-(quinolin-8-yl)thiophene-2-sulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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