CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2471
Family Name NF-kappa-B Inhibitor 2-nitro-n-(quinolin-8-yl)benzenesulfonamide Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00268925 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 6 Ligand SB-742457 Superfamily
Class Class 8

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Neuronal acetylcholine receptor subunit alpha-4 Ligand Varenic... 3 54
Acetylcholinesterase Inhibitor Tacrine Family 12 515
5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
Rho-associated protein kinase 1 Inhibitor Rho-kinase Inhibitor... 6 39
Neuropeptide Y receptor type 1 Ligand PD-160170 Family 1 11
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
Histone deacetylase 6 Inhibitor N-(quinolin-3-yl)-6-(sulfamoyl... 4 8
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
NF-kappa-B Inhibitor 9-chloro-5h-6-thia-4,5-diaza-chrysene 6,6... 3 27
NF-kappa-B Inhibitor 5-bromo-n-(quinolin-8-yl)thiophene-2-sulf... 2 5
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 4
Neuropeptide Y receptor type 5 and Neuropeptide Y receptor typ... 1 0
Lysine-specific demethylase 4E and Lethal(3)malignant brain tu... 1 1
Cytochrome P450 3A4 inhibitor N-[2-fluoro-4-(4-fluorophenyl)ph... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00268923 DNC008184 Investigative Drug 4-nitro-N-(quinolin-8-yl)benzenesulfonamide
CFAMM00268925 DNC008183 Investigative Drug 2-nitro-N-(quinolin-8-yl)benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44589 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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