CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name NF-kappa-B Inhibitor 2-oxoguaia-1,4,11(13)-trien-12,8alpha-olide Family
No. of Seeds 4 No. of Other Members 18
Family Centroid CFAMM00185556 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily NF-kappa-B Binder Superfamily
Class Class 1490

Cousin Family NamesSeedsMembers
Arglabin family 4 38
Santonin family 1 23
Fatty acid synthase and Carnitine O-palmitoyltransferase 1, mu... 1 1
NF-kappa-B Inhibitor Miller-9z-enolide Family 10 147
NF-kappa-B Inhibitor Helenalinmethacrylate Family 3 17
UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor Eu... 3 1
Aromatase Inhibitor 11beta,13-dihydro-10-epi-8-deoxycumam-brin... 1 8
Trypsin-1 and Prothrombin inhibitor (3S,3aR,6aS)-3-(4-methyl-2... 1 3


External ID

Functional Category

Molecule Name

CFAMM00185555 DNC006365 Investigative Drug 2-oxoguaia-1,4(15), 11(13)-trien-12,8beta-olide
CFAMM00185571 DNC010807 Investigative Drug DEHYDROLEUCODIN
CFAMM00185541 DNC000465 Investigative Drug Costunolide
CFAMM00185556 DNC006364 Investigative Drug 2-oxoguaia-1,4,11(13)-trien-12,8alpha-olide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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