CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2486
Family Name Calcium-activated potassium channel subunit alpha-1 Ligand Triphenylacetic Acid Methyl Ester Family
No. of Seeds 1 No. of Other Members 10
Family Centroid CFAMM00269373 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Calcium-activated potassium channel subunit alpha-1 Ligand Triphenylacetic Acid Methyl Ester Superfamily
Class Class 84

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
Muscarinic acetylcholine receptor Ligand Cyclopentolate Family 10 11
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-c... 4 43
Prostaglandin G/H synthase 1 Inhibitor 2-(3'-ethylsulfanyl-bip... 1 4
Fatty-acid amide hydrolase 1 Inhibitor Btnp Family 1 7
Trypsin-1 and Prothrombin inhibitor (3S,3aR,6aS)-3-benzyl-3,3a... 2 23
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[9-... 2 15
Aldo-keto reductase family 1 member C3 inhibitor (8R,9S,13S,14... 2 0
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Peroxisome proliferator-activated receptor gamma ligand SureCN... 3 3
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Metabotropic glutamate receptor 1 ligand SureCN186260 family 1 4
Sodium-dependent dopamine transporter inhibitor AGN-PC-074TA8 ... 2 5
Aromatic Homomonocyclic Compounds Metabolite Dimethylbenzyl ca... 2 11
Carboxylic Acids and Derivatives Metabolite 3-Acetoxy-3-methyl... 2 0
Putative NP ZINC06763537 Family 6 4
7a-hydroxy-7-phenyl-3,3a,4,5,6,7-hexahydro-1-benzofuran-2-one ... 4 0
Putative NP ZINC02930279 Family 2 1


External ID

Functional Category

Molecule Name

CFAMM00269373 DNC008275 Investigative Drug triphenylacetic acid methyl ester

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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